Specification
| Description | Recombinant protein from the full-length sequence of homo sapiens complement factor H related 1 (CFHR1) (NM_002113). |
| Organism | Homo sapiens (Human) |
| Expression Host | Human Cells |
| Tag Info | His or DYKDDDDK. Please contact us if you need further information or require specific designed tag. |
| Purity | Greater than 90% by SDS-PAGE gel |
| Uniprot ID | Q03591 |
| Entry Name | FHR1_HUMAN |
| Gene Names | CFHR1 CFHL CFHL1 CFHL1P CFHR1P FHR1 HFL1 HFL2 |
| Alternative Gene Names | CFHL CFHL1 CFHL1P CFHR1P FHR1 HFL1 HFL2 |
| Alternative Protein Names | Complement factor H-related protein 1 (FHR-1) (H factor-like protein 1) (H-factor-like 1) (H36) |
| Application | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only! |
| Buffer | Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives |
| Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
| Length | 330 |
| Molecular Weight(Da) | 37651 |
| Protein Sequence | (The sequence of expressed protein may have some variation from the sequence shown below. Please contact us for the exact sequence.) MWLLVSVILISRISSVGGEATFCDFPKINHGILYDEEKYKPFSQVPTGEVFYYSCEYNFVSPSKSFWTRITCTEEGWSPTPKCLRLCFFPFVENGHSESSGQTHLEGDTVQIICNTGYRLQNNENNISCVERGWSTPPKCRSTDTSCVNPPTVQNAHILSRQMSKYPSGERVRYECRSPYEMFGDEEVMCLNGNWTEPPQCKDSTGKCGPPPPIDNGDITSFPLSVYAPASSVEYQCQNLYQLEGNKRITCRNGQWSEPPKCLHPCVISREIMENYNIALRWTAKQKLYLRTGESAEFVCKRGYRLSSRSHTLRTTCWDGKLEYPTCAKR |
Background
| Function | FUNCTION: Involved in complement regulation. The dimerized forms have avidity for tissue-bound complement fragments and efficiently compete with the physiological complement inhibitor CFH. Can associate with lipoproteins and may play a role in lipid metabolism. {ECO:0000269|PubMed:23487775}. |
| Pathway | |
| Protein Families | |
| Tissue Specificity | Expressed by the liver and secreted in plasma. |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |